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1

Scaffold oriented synthesis. Part 1: Design, preparation, and biological evaluation of thienopyrazoles as kinase inhibitors

Irini Akritopoulou-Zanze, Daria Darczak, Kathy Sarris, Kathleen M. Phelan, Jeffrey R. Huth, Danying Song, Eric F. Johnson, Yong Jia, Stevan W. Djuric

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 119 KB

english, 2006

2

Predicting protein druggability

Philip J. Hajduk, Jeffrey R. Huth, Christin Tse

Journal:

Drug Discovery Today

Year:

2005

Language:

english

File:

PDF, 487 KB

english, 2005

3

Novel p -Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based Improvement of Pharmaceutical Properties

Liu, Gang, Huth, Jeffrey R., Olejniczak, Edward T., Mendoza, Renaldo, DeVries, Peter, Leitza, Sandra, Reilly, Edward B., Okasinski, Gregory F., Fesik, Stephen W., von Geldern, Thomas W.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 440 KB

english, 2001

4

PRCI Ambient NO 2 AERMOD Performance Assessment and Model Improvement Project: Modeled to Observed Comparison

Panek, Jeffrey A., McCarthy, James M., Huth, Adrian Z., Krol, Alan J., Nowak, Christopher

Journal:

Journal of the Air & Waste Management Association (1995-)

Year:

2020

Language:

english

File:

PDF, 1.13 MB

english, 2020

5

Redox conditions for stimulation of in vitro folding and assembly of the glycoprotein hormone chorionic gonadotropin

Jeffrey R. Huth, Feng Weijun, Raymond W. Ruddon

Journal:

Biotechnology and Bioengineering

Year:

1994

Language:

english

File:

PDF, 771 KB

english, 1994

6

NMR in Pharmacokinetic and Pharmacodynamic Profiling

Chaohong Sun, Jeffrey R. Huth, Philip J. Hajduk

Journal:

Year:

2005

Language:

english

File:

PDF, 322 KB

english, 2005

7

Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket

Kent D. Stewart, Jeffrey R. Huth, Teresa I. Ng, Keith McDaniel, Rebecca Newlin Hutchinson, Vincent S. Stoll, Renaldo R. Mendoza, Edmund D. Matayoshi, Robert Carrick, HongMei Mo, Jean Severin, Karl Wal

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 687 KB

english, 2010

8

Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms

Jie Qian, Martin J Voorbach, Jeffrey R Huth, Michael L Coen, Haichao Zhang, Shi-Chung Ng, Kenneth M Comess, Andrew M Petros, Saul H Rosenberg, Usha Warrior, David J Burns

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 512 KB

english, 2004

9

Scaffold oriented synthesis. Part 2: Design, synthesis and biological evaluation of pyrimido-diazepines as receptor tyrosine kinase inhibitors

Vijaya Gracias, Zhiqin Ji, Irini Akritopoulou-Zanze, Cele Abad-Zapatero, Jeffrey R. Huth, Danying Song, Philip J. Hajduk, Eric F. Johnson, Keith B. Glaser, Patrick A. Marcotte, Lori Pease, Nirupama B.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 437 KB

english, 2008

10

Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR

Andrew M. Petros, Jeffrey R. Huth, Thorsten Oost, Cheol-Min Park, Hong Ding, Xilu Wang, Haichao Zhang, Paul Nimmer, Renaldo Mendoza, Chaohong Sun, Jamey Mack, Karl Walter, Sarah Dorwin, Emily Gramling

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.84 MB

english, 2010

11

N-Aryl-benzimidazolones as novel small molecule HSP90 inhibitors

Milan Bruncko, Stephen K. Tahir, Xiaohong Song, Jun Chen, Hong Ding, Jeffrey R. Huth, Sha Jin, Russell A. Judge, David J. Madar, Chang H. Park, Cheol-Min Park, Andrew M. Petros, Christin Tse, Saul H.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 688 KB

english, 2010

12

A fluorometric high performance liquid chromatographic assay for Vanillylmandelic acid (VMA) developed from a commercial kit method

Jeffrey A. Huth, Peggy L. Bottjen, Carl W. Ludvigsen

Journal:

Clinical Biochemistry

Year:

1986

Language:

english

File:

PDF, 446 KB

english, 1986

13

Direct assay for creatine kinase by reversed-phase high-performance liquid chromatography

Neil D. Danielson, Jeffrey A. Huth

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1980

Language:

english

File:

PDF, 740 KB

english, 1980

14

Design of an expression system for detecting folded protein domains and mapping macromolecular interactions by NMR

Jeffrey R. Huth, Carole A. Bewley, G. Marius Clore, Angela M. Gronenborn, Belinda M. Jackson, Alan G. Hinnebusch

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 3.89 MB

english, 1997

15

Enhancement of chemical rules for predicting compound reactivity towards protein thiol groups

James T. Metz, Jeffrey R. Huth, Philip J. Hajduk

Journal:

Journal of Computer-Aided Molecular Design

Year:

2007

Language:

english

File:

PDF, 161 KB

english, 2007

16

Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery

Kent D. Stewart, Kevin Steffy, Kevin Harris, John E. Harlan, Vincent S. Stoll, Jeffrey R. Huth, Karl A. Walter, Emily Gramling-Evans, Renaldo R. Mendoza, Jean M. Severin, Paul L. Richardson, Leo W. Ba

Journal:

Journal of Computer-Aided Molecular Design

Year:

2007

Language:

english

File:

PDF, 627 KB

english, 2007

17

dhNote

Rodney S. Markin, Michael C. Wadman, Peggy L. Bottjen, Mary C. Haven, Jeffrey A. Huth

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 469 KB

english, 1990

18

Discovery and Design of Novel HSP90 Inhibitors Using Multiple Fragment-based Design Strategies

Jeffrey R. Huth, Chang Park, Andrew M. Petros, Aaron R. Kunzer, Michael D. Wendt, Xilu Wang, Christopher L. Lynch, Jamey C. Mack, Kerry M. Swift, Russell A. Judge, Jun Chen, Paul L. Richardson, Sha Ji

Journal:

Chemical Biology & Drug Design

Year:

2007

Language:

english

File:

PDF, 671 KB

english, 2007

19

The solution structure of an HMG-I(Y)–DNA complex defines a new architectural minor groove binding motif

Huth, Jeffrey R., Bewley, Carole A., Nissen, Mark S., Evans, Jeremy N.S., Reeves, Raymond, Gronenborn, Angela M., Clore, G. Marius

Journal:

Natural Structural Biology

Year:

1997

File:

PDF, 1.13 MB

1997

20

Molecular determinants ofmammalian sex

Milton H. Werner, Jeffrey R. Huth, Angela M. Gronenborn, G. Marius Clore

Journal:

Trends in Biochemical Sciences

Year:

1996

Language:

english

File:

PDF, 881 KB

english, 1996

21

Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NFκB

Jun Qin, G.Marius Clore, WM Poindexter Kennedy, Jeffrey R Huth, Angela M Gronenborn

Journal:

Year:

1995

Language:

english

File:

PDF, 1.17 MB

english, 1995

22

Performance of Room Temperature Mercuric Iodide (Hgi2) Detectors in the Ultralow-Energy X-Ray Region

Dabrowski, Andrzej J., Iwanczyk, Jan S., Barton, Jeffrey B., Huth, Gerald C., Whited, Richard, Ortale, Carol, Economou, Thanasis E., Turkevich, Anthony L.

Journal:

IEEE Transactions on Nuclear Science

Year:

1981

Language:

english

File:

PDF, 973 KB

english, 1981

23

Druggability Indices for Protein Targets Derived from NMR-Based Screening Data

Hajduk, Philip J., Huth, Jeffrey R., Fesik, Stephen W.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 322 KB

english, 2005

24

ALARM NMR: A Rapid and Robust Experimental Method To Detect Reactive False Positives in Biochemical Screens

Huth, Jeffrey R., Mendoza, Renaldo, Olejniczak, Edward T., Johnson, Robert W., Cothron, Darlene A., Liu, Yaya, Lerner, Claude G., Chen, Jun, Hajduk, Philip J.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 175 KB

english, 2005

25

METOPROLOL VERSUS CARVEDILOL ON OUTCOME IN MADIT-CRT

Ruwald, Martin Huth, Ruwald, Anne-Christine, Jøns, Christian, Alexis, Jeffrey, McNitt, Scott, Zareba, Wojciech, Moss, Arthur

Journal:

Journal of the American College of Cardiology

Year:

2013

Language:

english

File:

PDF, 245 KB

english, 2013

26

The Wing of the Enhancer-Binding Domain of Mu Phage Transposase is Flexible and is Essential for Efficient Transposition

Robert T. Clubb, Michiyo Mizuuchi, Jeffrey R. Huth, James G. Omichinski, Harri Savilahti, Kiyoshi Mizuuchi, G. Marius Clore and Angela M. Gronenborn

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 989 KB

english, 1996

27

Derivatization of Kel-F particles with n-butyllithium for liquid chromatography

Huth, Jeffrey A., Danielson, Neil D.

Journal:

Analytical Chemistry

Year:

1982

Language:

english

File:

PDF, 616 KB

english, 1982

28

NMR-Driven Discovery of Benzoylanthranilic Acid Inhibitors of Far Upstream Element Binding Protein Binding to the Human Oncogene c-myc Promoter

Huth, Jeffrey R., Yu, Liping, Collins, Irene, Mack, Jamey, Mendoza, Renaldo, Isaac, Binumol, Braddock, Demetrios T., Muchmore, Steven W., Comess, Kenneth M., Fesik, Stephen W., Clore, G. Marius, Leven

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 350 KB

english, 2004

29

Discovery of Novel p -Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 4. Structure−Activity Relationship of Substituents on the Benzene Ring of the Cinnamide

Winn, Martin, Reilly, Edward B., Liu, Gang, Huth, Jeffrey R., Jae, Hwan-Soo, Freeman, Jennifer, Pei, Zhonghua, Xin, Zhili, Lynch, John, Kester, Jeff, von Geldern, Thomas W., Leitza, Sandra, DeVries, P

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 213 KB

english, 2001

30

Toxicological Evaluation of Thiol-Reactive Compounds Identified Using a La Assay To Detect Reactive Molecules by Nuclear Magnetic Resonance

Huth, Jeffrey R., Song, Danying, Mendoza, Renaldo R., Black-Schaefer, Candice L., Mack, Jamey C., Dorwin, Sarah A., Ladror, Uri S., Severin, Jean M., Walter, Karl A., Bartley, Diane M., Hajduk, Philip

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 345 KB

english, 2007

31

Reactivity of Kel-F polymers with organolithium and organomagnesium compounds

Danielson, Neil D., Taylor, Richard T., Huth, Jeffrey A., Siergiej, Richard W., Galloway, James G., Paperman, Joseph B.

Journal:

Industrial & Engineering Chemistry Product Research and Development

Year:

1983

Language:

english

File:

PDF, 617 KB

english, 1983

32

Combination of the Chorionic Gonadotropin Free β-Subunit with α*

BEEBE, JEAN SACCUZZO, HUTH, JEFFREY R., RUDDON, RAYMOND W.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.28 MB

english, 1990

33

Vitamin supplements and purported learning enhancement in mentally retarded children.

MENOLASCINO, Frank J., DONALDSON, John Y., GALLAGHER, Thomas F., GOLDEN, Charles J., WILSON, James E., HUTH, Jeffrey A., LUDVIGSEN, Carl W., GILLETTE, Daniel W.

Journal:

Journal of Nutritional Science and Vitaminology

Year:

1989

Language:

english

File:

PDF, 1.28 MB

english, 1989

34

Long-Term Survival after Complete Surgical Resection and Adjuvant Immunotherapy for Distant Melanoma Metastases

Faries, Mark B., Mozzillo, Nicola, Kashani-Sabet, Mohammed, Thompson, John F., Kelley, Mark C., DeConti, Ronald C., Lee, Jeffrey E., Huth, James F., Wagner, Jeffrey, Dalgleish, Angus, Pertschuk, Danie

Journal:

Annals of Surgical Oncology

Year:

2017

Language:

english

File:

PDF, 636 KB

english, 2017

35

Five Dimensional X-ray Imaging with the Color X-ray Camera

Davis, Jeffrey M., Schmidt, Julia, Huth, Martin, Hartman, Robert, Soltau, Heike, Striider, Lothar

Journal:

Microscopy and Microanalysis

Year:

2017

Language:

english

File:

PDF, 1.53 MB

english, 2017

36

Processing a Five Dimensional X-ray Image: Big Data Challenges and Opportunities

Davis, Jeffrey M., Schmidt, Julia, Huth, Martin, Hartman, Robert, Soltau, Heike, Strüder, Lothar

Journal:

Microscopy and Microanalysis

Year:

2017

Language:

english

File:

PDF, 3.61 MB

english, 2017

37

Analysis of Polymorphs Using Simultaneous X-ray Fluorescence and Diffraction with an Imaging Spectrometer

Davis, Jeffrey M., Schmidt, Julia, Huth, Martin, Hartmann, Robert, Ihle, Sebastian, Steigenhöfer, Daniel, Soltau, Heike, Strüder, Lothar

Journal:

Microscopy and Microanalysis

Year:

2016

Language:

english

File:

PDF, 746 KB

english, 2016

38

Micro-Focused Five Dimensional X-ray Imaging with the Color X-ray Camera

Davis, Jeffrey M., Schmidt, Julia, Huth, Martin, Hartmann, Robert, Soltau, Heike, Strüder, Lothar

Journal:

Microscopy and Microanalysis

Year:

2018

Language:

english

File:

PDF, 1.39 MB

english, 2018

39

CRC Handbook of Clinical Chemistry (CRC Series in Clinical Laboratory, Science) 1, M. Werner, Ed., CRC Press, Inc., Boca Raton, FL 33431, 1982, 559 pp, $96.00 in U.S.; $110 outside U.S. ISBN 0-8493-7080-9

Burritt, Mary F, Faynor, Steven M, Huth, Jeffrey A

Journal:

Clinical Chemistry

Year:

1983

File:

PDF, 234 KB

1983